What imaging finding is characteristic of Crohn's disease?

The characteristic imaging finding of Crohn's disease is a curved, cobblestone appearance. This appearance is associated with the irregular, transmural involvement of the bowel that is typical in Crohn's disease. On imaging studies such as CT scans or MRI, the affected segments of the intestine may show a series of deep ulcerations and fissures, which contribute to this cobblestone pattern. This finding is very specific to Crohn's disease and helps differentiate it from other gastrointestinal conditions such as ulcerative colitis.

In contrast, ring-enhancing lesions are more commonly associated with abscess formation or other processes, while wall thickening alone could be seen in various conditions affecting the intestine. Air-fluid levels may indicate an obstruction or perforation but are not specific to Crohn's. Therefore, the cobblestone appearance is a key feature used by clinicians to diagnose and manage Crohn's disease effectively.