What finding correlates with a higher rate of aneurysm rupture in patients with a history of smoking?

Current tobacco usage is associated with a higher rate of aneurysm rupture due to its direct deleterious effects on the vascular system. Smoking contributes to the remodeling of blood vessels and accelerates the processes of atherosclerosis. It is known to increase inflammation, weaken vessel walls, and promote thrombosis, all of which can significantly heighten the risk of aneurysm formation and rupture.

Chronic exposure to the harmful substances in tobacco smoke can lead to endothelial dysfunction and changes in hemodynamics, thus exacerbating the risk of aneurysm complications. Therefore, individuals who continue to smoke are at a markedly increased risk for adverse outcomes related to existing aneurysms.

While factors like age over 70, high cholesterol levels, and hypertensive emergencies also contribute to cardiovascular risks, the direct and acute impact of current tobacco usage on aneurysm stability makes it the most relevant factor in this context.